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What is XELJANZ/XELJANZ XR?

XELJANZ/XELJANZ XR (tofacitinib) is a prescription medicine called a Janus kinase (JAK) inhibitor used to treat:

  • Adults with moderately to severely active rheumatoid arthritis in whom methotrexate did not work well or cannot be tolerated
  • Adults with active psoriatic arthritis in which methotrexate or other similar medicines called nonbiologic disease-modifying antirheumatic drugs (DMARDs) did not work well or cannot be tolerated

It is not known if XELJANZ/XELJANZ XR is safe and effective in children or in people with Hepatitis B or C.

XELJANZ/XELJANZ XR is not recommended for people with severe liver problems.

TRIAL Rx PROGRAM TERMS
AND CONDITIONS

  • This is not health insurance and is a one-time-only offer for eligible, commercially insured patients.
  • Offer is only available to patients who have been diagnosed with an FDA-approved indication for XELJANZ® XR (tofacitinib citrate) extended release.
  • Patients who have already begun therapy with XELJANZ XR at the time of the request and patients under the age of eighteen (18) years of age are ineligible for participation in the Program.
  • No claim for reimbursement for product dispensed pursuant to this offer may be submitted to any third-party private payer.
  • Not available to patients covered under government plans such as Medicaid, Medicare, or other federal or state healthcare programs, including any state prescription drug assistance programs and the Government Health Insurance Plan or for residents of Massachusetts.
  • Available in a 14-day supply.
  • This offer does not require, nor will be made contingent on, purchase requirements of any kind.
  • Pfizer reserves the right to amend, rescind, or discontinue this program at any time without notification.
  • Trial Rx can only be dispensed by the exclusive pharmacy and only after benefits investigation has been completed.
  • Additional eligibility criteria may apply. Contact XELSOURCE for details.

If you have questions or are in need of additional support, call 1-855-493-5526 or visit www.XELJANZ.com.

Pfizer Inc, 235 E. 42nd Street, New York, NY 10017

Please see full Prescribing Information, including BOXED WARNING and Medication Guide.

XELSOURCE & XELJANZ ACCESS TERMS & CONDITIONS

PFIZER PATIENT ASSISTANCE PROGRAM ELIGIBILITY CRITERIA

  • The Pfizer Patient Assistance Program is not health insurance and is available for eligible uninsured/underinsured patients only.
  • Offer is only available to patients who meet financial and other criteria.
  • This offer does not require, nor will it be made contingent on, purchase requirements of any kind.
  • No claim for reimbursement or credit for any costs associated with the medicine(s) may be submitted to any prescription insurance provider or payer, including Medicare Part D plans.
  • Pfizer reserves the right to amend, rescind, or discontinue this program at any time without notification.
  • Offer good only in the US and Puerto Rico.
  • Patient must be a resident of the US or Puerto Rico.
  • Prescription must be provided by a healthcare provider licensed in the US or Puerto Rico.
  • Patient must be treated in the outpatient setting of care.
  • Additional eligibility criteria may apply. Contact XELSOURCE for details.

INTERIM CARE Rx PROGRAM TERMS & CONDITIONS

  • Interim Care Rx is not health insurance and is available for eligible, commercially insured patients only.
  • Offer is only available to patients who have been diagnosed with an FDA-approved indication for XELJANZ/XELJANZ XR.
  • No claim for reimbursement for product dispensed pursuant to this offer may be submitted to any third-party payer.
  • Not available to patients covered under government plans such as Medicaid, Medicare or other federal or state healthcare programs, including any state prescription drug assistance programs and the Government Health Insurance Plan or for residents of Massachusetts, Michigan, Minnesota, Missouri, Ohio, or Rhode Island.
  • Available in 30-day supply. Refills are subject to limitations.
  • Interim Care Rx offer does not require, nor will be made contingent on, purchase requirements of any kind.
  • Pfizer reserves the right to amend, rescind, or discontinue this program at any time without notification.
  • Interim Care Rx can only be dispensed by the exclusive pharmacy and only after benefits investigation has been completed and a delay occurs in the prior authorization or appeals process.
  • Offer good only in the US and Puerto Rico.
  • Prescription must be provided by a healthcare provider licensed in the US or Puerto Rico.
  • Additional eligibility criteria may apply. Contact XELSOURCE for details.

VOUCHER TERMS AND CONDITIONS

By redeeming this voucher, you acknowledge that you currently meet the eligibility criteria and will comply with the terms & conditions described below:

  • You will receive a one-time, 30-day supply of XELJANZ.
  • Only new patients may use this voucher. By redeeming this voucher, you certify that you are not currently using XELJANZ.
  • An original voucher and a valid prescription must be presented to the pharmacy.
  • The voucher will be accepted only at participating pharmacies.*
  • You must not submit any claim for reimbursement for product dispensed pursuant to this voucher to any third-party payor, including Medicare, Medicaid, or any other federal or state health care program. You cannot apply the value of the free product received through this voucher toward any government insurance benefit out-of-pocket spending calculations, such as Medicare Part D True Out-of-Pocket Costs (TrOOP).
  • You must be 18 years of age or older to redeem this voucher.
  • This voucher is not valid where prohibited by law.
  • This voucher cannot be combined with any other savings, free trial or similar offer for the specified prescription. This voucher should not be combined with samples for the specified prescription.
  • This free trial voucher is not health insurance. This free trial voucher is not intended to address delays or gaps in health insurance coverage for the specified prescription.
  • Offer good only in the U.S. and Puerto Rico.
  • No purchase is necessary.
  • Patients have no obligation to continue to use XELJANZ.
  • Pfizer reserves the right to rescind, revoke, or amend this offer without notice.
  • This voucher expires 12/31/2021.

*MA residents may select their pharmacy. Otherwise, this free trial will be supplied through XELSOURCE.

CO-PAY CARD TERMS AND CONDITIONS

By using the XELJANZ/XELJANZ XR Co-pay Savings Card (the “Card”), you acknowledge that you currently meet the eligibility criteria and will comply with the following terms and conditions.

  • Patients are not eligible to use this card if they are enrolled in a state- or federally-funded insurance program, including but not limited to Medicare, Medicaid, TRICARE, Veteran Affairs health care, a state prescription drug assistance program, or the Government Health Insurance Plan available in Puerto Rico (formerly known as “La Reforma de Salud”).
  • Patient must have private insurance. Offer is not valid for cash paying patients.
  • You will receive a maximum benefit of $15,000 per calendar year, which is defined by the date of enrollment through December 31st of the enrollment year, and may pay as little as $0 per month co-pay. After a maximum of $15,000, you will be responsible for paying the remaining monthly out-of-pocket costs.
  • This Card is not valid when the entire cost of your prescription drug is eligible to be reimbursed by your private insurance plan or other private health or pharmacy benefit programs.
  • You must deduct the value of this coupon from any reimbursement request submitted to your insurance plan, either directly by you or on your behalf.
  • You are responsible for reporting use of the Card to any private insurer, health plan, or other third party who pays for or reimburses any part of the prescription filled using the Card, as may be required. You should not use the Card if your insurer or health plan prohibits use of manufacturer Cards.
  • You must be 18 years of age or older to redeem the Card.
  • The Card is not valid where prohibited by law.
  • The Card cannot be combined with any other savings, free trial, or similar offer for the specified prescription.
  • The Card will be accepted only at participating pharmacies.
  • If your pharmacy does not participate, you may be able to submit a request for a rebate in connection with this offer.
  • The Card is not health insurance.
  • Offer good only in the US and Puerto Rico.
  • The Card is limited to 1 per person during this offering period and is not transferable.
  • The Card may be used once per month for the life of the program.
  • No other purchase is necessary.
  • Data related to your redemption of the Card may be collected, analyzed, and shared with Pfizer, for market research and other purposes related to assessing Pfizer’s programs. Data shared with Pfizer will be aggregated and de-identified; it will be combined with data related to other Card redemptions and will not identify you.
  • Pfizer reserves the right to rescind, revoke, or amend the program without notice.
  • Card and Program expires 12/31/2019.

XSAVINGS Mobile Text Program Terms & Conditions

User texts "XPROGRAM" to short code 50336.
Text HELP for help, STOP to opt out.
Patients may receive up to 10 messages per month.
Message and data rates may apply.

  1. By opting into the XSAVINGS mobile texting program (Program), you consent to receive up to 10 text messages and/or push notifications from Pfizer Inc. Such messages may be marketing or non-marketing messages and may include co-pay related information, fill confirmation, website information, etc.
  2. To stop receiving text messages, text STOP to 50336. DOING SO WILL ONLY OPT YOU OUT OF THIS PROGRAM; you will remain opted in to any other Pfizer Inc text message program(s) into which you opted separately.
  3. To request more information or to obtain help, text HELP to 50336. You can also call customer service at 1-844-935-5269.
  4. You represent that you are the account holder for the mobile telephone number(s) that you provide to opt into the Program. You are responsible for notifying Pfizer Inc immediately if you change your mobile telephone number. You may notify Pfizer Inc of a number change by calling 1-844-935-5269.
  5. Message and data rates may apply to each text message sent or received in connection with the texting program, as provided in your mobile telephone service rate plan (please contact your mobile telephone carrier for pricing plans). Applicable roaming charges may apply. Charges are both billed and payable to your mobile service provider or deducted from your prepaid account. Pfizer Inc does not impose a separate fee for sending text messages.
  6. Data obtained from you in connection with this Program may include your telephone number, your carrier's name, and details of the message (date, time, and content). Pfizer Inc may use this information to contact you and to provide the services you request.
  7. For information on data collection and use, please read our full corporate Privacy Policy (https://www.pfizer.com/Privacy), which is incorporated by reference into these Terms.
  8. Pfizer Inc will not be liable for any delays in the receipt of any SMS messages, as delivery is subject to effective transmission from your network operator.
  9. This Program is available only on these US participating mobile carriers: Verizon Wireless, Sprint, Boost Mobile, T-Mobile, AT&T, Atlantic Tele-Network International (ATNI), Alaska Communications Systems (ACS), ASTAC, Bandwidth.com (includes Republic Wireless), Blue Wireless, Bluegrass Cellular, Breakaway Wireless, Brightlink, C Spire Wireless (aka Cellular South), Carolina West Wireless, CellCom, Cellone Nation, Cellular One of N.E. Arizona, Chariton Valley Cellular, Chat Mobility, Copper Valley Telecom, Cordova Wireless, Cross Wireless, CTC, Custer Telephone, East Kentucky Network (Appalachian Wireless), Enflick, GCI Communications, Google Voice, Illinois Valley Cellular, Inland Cellular, Inteliquent, iWireless, Leaco Rural Telephone Cooperative, Limitless Mobile, Mid-Rivers Communications, MobileNation/SI Wireless, MTA Wireless/Matanuska Kenai, Nemont CDMA, Nemont US UMTS, NewCore Wireless, Nex-Tech Wireless, NNTC Wireless, Northwest Missouri Cellular, Pine Belt Wireless, Pine Cellular, Pioneer Cellular, PTCI, Shelcomm, Silver Star PCS, Snake River PCS, SouthernLINC, SouthernLINC LTE, SRT, STRATA Networks, Standing Rock (SRTI), Thumb Cellular, Triangle Wireless, Union Wireless, U.S. Cellular, United Wireless, Viaero Wireless, Virgin Mobile, West Central Wireless.
  10. You agree to indemnify Pfizer Inc and any third parties texting on its behalf in full for all claims, expenses, and damages related to or caused, in whole or in part, by your failure to immediately notify us if you change your telephone number, including but not limited to all claims, expenses, and damages related to or arising under the Telephone Consumer Protection Act.
  11. Pfizer Inc may immediately suspend or terminate your participation in the Program if it believes you are in breach of these SMS Terms and Conditions. Your participation in this Program is also subject to termination in the event that your mobile telephone service terminates or lapses. Pfizer Inc reserves the right to modify or discontinue, temporarily or permanently, all or any part of the Program, with or without notice.
  12. Pfizer Inc may revise, modify, or amend these SMS Terms and Conditions at any time. Any such revision, modification, or amendment shall take effect when it is posted to Pfizer Inc's website. You agree to review these SMS Terms and Conditions periodically to ensure that you are aware of any changes. Your continued consent to receive text messages will indicate your acceptance of those changes.

If you have questions or are in need of additional support, call 1-844-935-5269 or visit www.XELJANZ.com.

Taking XELJANZ & XELJANZ XR

One of the differences is how many times a day you take it—XELJANZ XR is the once-daily formulation of XELJANZ. If you’re currently taking XELJANZ but are interested in a once-daily treatment, talk with your doctor about XELJANZ XR. In the meantime, learn more about the two with the chart below.

XELJANZ XELJANZ XR
HOW IT'S TAKEN
Twice a day with or without food Once a day with or without food*
DOSAGE FORMS AND STRENGTHS
5 mg tablet 11 mg extended-release tablet
HOW IT'S DELIVERED
Immediate release into the bloodstream over the course of several hours Extended release into the bloodstream over the course of a day
RHEUMATOLOGY INDICATIONS
  • Active psoriatic arthritis†
  • Moderate to severe
    rheumatoid arthritis
  • Active psoriatic arthritis†
  • Moderate to severe
    rheumatoid arthritis

*XELJANZ XR tablets should be swallowed whole and intact. Do not crush, split, or chew.

†For active psoriatic arthritis (PsA), XELJANZ and XELJANZ XR should be taken with a disease-modifying antirheumatic drug (DMARD), such as methotrexate.

About XELJANZ & XELJANZ XR

At your next appointment, ask your doctor if XELJANZ/XELJANZ XR could be right for you. XELJANZ/XELJANZ XR is taken in combination with methotrexate, sulfasalazine or leflunomide. To start the conversation, drag and drop these questions to rearrange them in order of importance to you. Then make sure to share the list with your doctor.
  • What is the most important risk information I need to know about XELJANZ/XELJANZ XR?
  • I have heard that XELJANZ/XELJANZ XR is an UNJECTIONTM, one of a number of oral treatment options that is not an injection or infusion. Could adding it to a nonbiologic DMARD like methotrexate be an option for me?
  • What side effects might I experience with XELJANZ/XELJANZ XR?
  • If some patients taking XELJANZ or XELJANZ XR with a nonbiologic DMARD felt an improvement in psoriatic arthritis symptoms and physical functioning at 3 months, do you think I could experience similar results?
  • XELJANZ/XELJANZ XR can help improve physical function. Why is this important?
  • What should I do if I forget to take any of my pills?
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QUESTIONS
EMAIL QUESTIONS
How can I learn if XELJANZ/XELJANZ XR could be right for me?

If you’re not getting enough relief of joint pain and swelling with a nonbiologic disease-modifying antirheumatic drug (DMARD) like methotrexate, adding XELJANZ/XELJANZ XR could help. If you've tried a biologic DMARD and it didn't work well enough, starting on XELJANZ XR plus a nonbiologic DMARD may be an option.

Talk to your doctor to find out if XELJANZ/XELJANZ XR could be right for you.

How does XELJANZ XR work?

As a JAK inhibitor, XELJANZ XR works to disrupt cell activities believed to play a role in inflammation associated with psoriatic arthritis.

How soon may I notice a difference when taking XELJANZ/XELJANZ XR?

In some patients in the clinical studies, XELJANZ began to work in as early as 2 weeks to help relieve joint pain and swelling. For others, it can take as long as 3 to 6 months. Results were seen for patients taking XELJANZ in combination with a nonbiologic DMARD. Everybody is different though, so your results may vary.

Learn more about how XELJANZ performed in Clinical Studies. XELJANZ/​XELJANZ XR may also cause serious side effects. Learn more about the most important information you should know about XELJANZ/​XELJANZ XR.

What are the active ingredients in XELJANZ/XELJANZ XR?

The active ingredient in XELJANZ/XELJANZ XR is tofacitinib.

What laboratory tests are necessary with XELJANZ/XELJANZ XR?

Your healthcare provider should do blood tests before you start receiving XELJANZ/XELJANZ XR, and while you take XELJANZ/XELJANZ XR, to check for the following:

  • Changes in lymphocyte counts. Lymphocytes are white blood cells that help the body fight off infections.
  • Low neutrophil counts. Neutrophils are white blood cells that help the body fight off infections.
  • Low red blood cell count. This may mean that you have anemia, which may make you feel weak and tired.
  • Your healthcare provider should test you for TB before starting XELJANZ/XELJANZ XR and during treatment.

Your healthcare provider should routinely check certain liver tests.

You should not receive XELJANZ/XELJANZ XR if your lymphocyte count, neutrophil count, or red blood cell count is too low or your liver tests are too high. Your healthcare provider may stop your XELJANZ/XELJANZ XR treatment for a period of time if needed because of changes in these blood test results.

You may also have changes in other laboratory tests, such as your blood cholesterol levels. Your healthcare provider should do blood tests to check your cholesterol levels 4 to 8 weeks after you start XELJANZ/XELJANZ XR, and as needed after that.

How do I take XELJANZ/XELJANZ XR—does it require an injection or infusion?

XELJANZ/XELJANZ XR is a pill taken by mouth. It is not an injection or infusion—it's an UNJECTIONTM. XELJANZ is taken twice daily while XELJANZ XR is taken once daily. XELJANZ/XELJANZ XR can be taken with or without food. For active psoriatic arthritis, XELJANZ and XELJANZ XR should be taken with a nonbiologic disease-modifying antirheumatic drug (DMARD), such as methotrexate.

For more information, see What Is XELJANZ/XELJANZ XR?

If I’m taking XELJANZ XR, will I see something in my stool?

When you take XELJANZ XR, you may see something in your stool that looks like a tablet. This is the empty shell from the tablet after the medicine has been absorbed by your body.

What should I do if I miss a dose?

Contact your healthcare provider if you miss a dose or forget to take XELJANZ/XELJANZ XR for an extended period of time.

What should I do if I am not seeing improvement in my symptoms?

Keep in mind that everybody is different. If you are not getting the results you expected, talk with your healthcare provider. Together, you can determine if changing your course of treatment might be an appropriate step.

What are some tips for remembering to take XELJANZ/XELJANZ XR?
  • Create daily reminders by using your mobile phone or sticky notes.
  • Set up alerts to remind you when it’s time to take XELJANZ/XELJANZ XR.
  • Take XELJANZ/XELJANZ XR with your morning and evening meals or before or after you brush your teeth in the morning. Take once-daily XELJANZ XR only in the morning or only in the evening.
What should I know before starting on XELJANZ/XELJANZ XR?

XELJANZ/XELJANZ XR can lower the ability of your immune system to fight infections. Some people can have serious infections while taking XELJANZ/XELJANZ XR, including tuberculosis (TB), and infections caused by bacteria, fungi, or viruses that can spread throughout the body. Some people have died from these infections.

  • Your healthcare provider should test you for TB before starting and during XELJANZ/XELJANZ XR treatment, and monitor you closely for signs and symptoms of TB infection during treatment.

You should not start taking XELJANZ/XELJANZ XR if you have any kind of infection unless your healthcare provider tells you it is okay. You may be at a higher risk of developing shingles (herpes zoster). People taking the higher dose (10 mg twice daily) of XELJANZ have a higher risk of serious infections and shingles.

What are the possible side effects of XELJANZ/XELJANZ XR?

XELJANZ/XELJANZ XR may cause serious side effects, including Hepatitis B or C activation infection in people who carry the virus in their blood. If you are a carrier of the Hepatitis B or C virus (viruses that affect the liver), the virus may become active while you use XELJANZ/XELJANZ XR. Your healthcare provider may do blood tests before you start treatment with XELJANZ/XELJANZ XR and while you are using XELJANZ/XELJANZ XR. Tell your healthcare provider if you have any of the following symptoms of a possible Hepatitis B or C infection: feel very tired, little or no appetite, clay-colored bowel movements, chills, muscle aches, skin rash, skin or eyes look yellow, vomiting, fevers, stomach discomfort, or dark urine.

These are not all the serious side effects of XELJANZ/XELJANZ XR.

To read more, see Important Safety Information. Patients should always ask their doctor for medical advice about adverse events.

What are common side effects of XELJANZ/XELJANZ XR?

Common side effects of XELJANZ/XELJANZ XR in rheumatoid arthritis and psoriatic arthritis patients include upper respiratory tract infections (common cold, sinus infections), headache, diarrhea, nasal congestion, sore throat, and runny nose (nasopharyngitis), and high blood pressure (hypertension).

These are not all the possible side effects of XELJANZ/XELJANZ XR.

To read more, see Important Safety Information.

What should I do if I experience side effects?

Patients should always ask their doctors for medical advice about side effects or adverse events. You are encouraged to report adverse events related to Pfizer products by calling 1-800-438-1985 (U.S. only). If you prefer, you may contact the U.S. Food and Drug Administration (FDA) directly. Visit www.fda.gov/MedWatch or call 1-800-FDA-1088.

Can I take XELJANZ/XELJANZ XR if I am pregnant or planning to have a baby?

Before starting XELJANZ/XELJANZ XR, be sure to talk with your healthcare provider if you plan to become pregnant or are pregnant. XELJANZ/XELJANZ XR may affect the ability of females to get pregnant. It is not known if this will change after stopping XELJANZ/XELJANZ XR. It is not known if XELJANZ/XELJANZ XR will harm an unborn baby.

  • Pregnancy Registry: Pfizer has a registry for pregnant women who take XELJANZ/XELJANZ XR. The purpose of this registry is to check the health of the pregnant mother and her baby. If you are pregnant or become pregnant while taking XELJANZ/XELJANZ XR, talk to your healthcare provider about how you can join this pregnancy registry or you may contact the registry at 1-877-311-8972 to enroll

For more information, see Important Safety Information.

Should I take XELJANZ/XELJANZ XR if I am breastfeeding or plan to breastfeed?

Before starting XELJANZ/XELJANZ XR, you and your healthcare provider should decide if you will take XELJANZ/XELJANZ XR or breastfeed. You should not do both. After you stop your treatment with XELJANZ/XELJANZ XR do not start breastfeeding again until 18 hours after your last dose of XELJANZ or 36 hours after your last dose of XELJANZ XR.

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