Explore Your Possibilities
Taken with a nonbiologic disease-modifying antirheumatic drug (DMARD), XELJANZ XR is a once-daily pill that can reduce joint pain and swelling and significantly improve physical function. Ask your doctor if XELJANZ XR could be right for you.
- How It Works
XELJANZ XR is the first and only Janus kinase (JAK) inhibitor approved for adults with active psoriatic arthritis. As a JAK inhibitor, XELJANZ XR works to disrupt cell activities believed to play a role in inflammation associated with psoriatic arthritis.
- Works With Nonbiologic DMARDs
If you’re not getting enough relief of joint pain and swelling with a nonbiologic DMARD like methotrexate, adding XELJANZ XR could help.
- Works Without Injections Or Infusions
XELJANZ XR is an
—it is not an injection or an infusion. If you’ve tried a biologic DMARD and it didn’t work well enough, starting on XELJANZ XR plus a nonbiologic DMARD may be an option.
Some examples of nonbiologic DMARDs that can be taken with
See the results of XELJANZ in Clinical Studies.
Taking XELJANZ & XELJANZ XR
One of the differences is how many times a day you take it—XELJANZ XR is the once-daily formulation of XELJANZ. If you’re currently taking XELJANZ but are interested in a once-daily treatment, talk with your doctor about XELJANZ XR. In the meantime, learn more about the two with the chart below.
XELJANZ | XELJANZ XR | ||
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5 mg tablet | 11 mg extended-release tablet | ||
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Immediate release into the bloodstream over the course of several hours | Extended release into the bloodstream over the course of a day | ||
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*XELJANZ XR tablets should be swallowed whole and intact. Do not crush, split, or chew.
†For active psoriatic arthritis (PsA), XELJANZ and XELJANZ XR should be taken with a disease-modifying antirheumatic drug (DMARD), such as methotrexate.