Enable JavaScript to visit this website.


Explore Your Possibilities

Taken with a nonbiologic disease-modifying antirheumatic drug (DMARD), XELJANZ XR is a once-daily pill that can reduce joint pain and swelling and significantly improve physical function. Ask your doctor if XELJANZ XR could be right for you.

  • How It Works

    XELJANZ XR is the first and only Janus kinase (JAK) inhibitor approved for adults with active psoriatic arthritis. As a JAK inhibitor, XELJANZ XR works to disrupt cell activities believed to play a role in inflammation associated with psoriatic arthritis.

  • Works With Nonbiologic DMARDs

    If you’re not getting enough relief of joint pain and swelling with a nonbiologic DMARD like methotrexate, adding XELJANZ XR could help.

  • Works Without Injections Or Infusions

    XELJANZ XR is an —it is not an injection or an infusion. If you’ve tried a biologic DMARD and it didn’t work well enough, starting on XELJANZ XR plus a nonbiologic DMARD may be an option.

XELJANZ/XELJANZ XR may also cause serious side effects. Learn more about the most important information you should know about XELJANZ/XELJANZ XR.

Some examples of nonbiologic DMARDs that can be taken with XELJANZ XR for adults with active psoriatic arthritis include:

Methotrexate Sulfasalazine Leflunomide
Methotrexate Sulfasalazine Leflunomide

See the results of XELJANZ in Clinical Studies.